Candida esophagitis may be treated orally or intravenously; for severe or azole-resistant esophageal candidiasis, treatment with amphotericin B may be necessary. Vaginal yeast infections are typically treated with topical antifungal agents. A one-time dose of fluconazole is 90% effective in treating a vaginal yeast infection. Yeast infection in mouth treatment depends on what is the cause of the infection. For this reason, the first step of the treatment, is identifying the cause of the yeast infection in mouth. Often overlooked, this is a critical part of the treatment since the needed treatment can be completely different. Before any treatment, you of course take a tongue swab lab test and then you know for sure if the fungus is present or not, and if it’s present, what the infection’ level, because treatment is in according to the level and also the fungus type, because there are .